There was also no weight loss plateau observed with CagriSema, with 43% of the patients achieving 15% weight loss and 24% achieving 20% weight loss
Originally developed to treat type 2 diabetes, medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) are now widely recognized for their ability to promote sustained, often significant, weight loss. Their mechanism is fascinatingthey mimic a naturally occurring hormone (glucagon-like peptide-1), which increases insulin secretion, suppresses glucagon, delays gastric emptying, and signals fullness to the brain
It wasnt until 2021 that compounded semaglutide was approved as a treatment for obesity
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Both are primarily injectable medications, although semaglutide can also be taken as a tablet called Rybelsus [2, 4, 5]