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NNK treatment significantly increases macrophage infiltration and expression of pro-inflammatory mediators such as macrophage inflammatory protein 1 alpha (MIP-1, interleukin 1 beta (IL-1), and TGF- in mice neoplastic lesions (117)

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While AAPI individuals made up approximately 16 percent of the citys population, they accounted for 37 percent of its home mortgage originations during this period