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The Nicotine Content of a Cigarette Doesnt Equal the Nicotine You Consume When Smoking Although its possible to use lab equipment to measure the nicotine content of a cigarette, the measurement achieved in this process isnt the same as the amount of nicotine that will enter your bloodstream when you smoke the cigarette

This question What is the healthiest thing to smoke? often arises among smokers looking to minimize harm

However, in vitro cytotoxicity assays are useful in determining the contribution of different tobacco blends or cigarette components (e.g., the filter) to the overall cytotoxicity of the smoke and in identifying causative cytotoxic agents in smoke and mechanistic pathways

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That dimension was specifically designed to not allow cigarette butts through, he says