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This was because the drug did not significantly reduce weight in 536 subjects over the course of 24 weeks 2

Furthermore, GLP-1 RAs have shown promise in reducing cancer risk, particularly in hormone-related malignancies such as breast and ovarian cancer

Starting on July 1, the temporary program is set to run for a year and a half through the end of 2027

Safety signals they share as a class Every FDA-approved GLP-1 receptor agonist and GIP/GLP-1 dual agonist carries the class boxed warning for thyroid C-cell tumor risk seen in rodent studies, and all are contraindicated with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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