Topiramate is associated with cognitive side effects including difficulty concentrating, memory problems, confusion, and slowed thinkingsometimes referred to colloquially as "Topamax fog"
However, studies of this type should be considered preliminary because the study lacked adequate control, including no randomization or placebo
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Tesamorelin can raise blood glucose in some people, especially if you already have prediabetes or insulin resistance, however studies show that those with diabetes on tesamorelin did not see a change in their glycemic control
Merck understands this, which is why it is focusing on the potential of HS-10535 not just for weight loss but also for offering additional cardiovascular and metabolic benefits
