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Plasma Metabolites as Possible Biomarkers for Diagnosis of Breast Cancer

NADP+/NADPH is a cofactor pair that provides active sources of protons and electrons and is closely linked with GSSG/GSH

Compared to the active state, ECL1 moves toward helix I by 5 when measured at the N-terminal tip of the helix (C of Q211), and ECL1 residue W214 is reoriented ~180 o from an outside-facing position to a position pointing towards helix I

Prostate 56:150161

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