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Some improvements were noted in specific symptoms for female participants, particularly in reducing thirst and fatigue, but these effects were not significant across the broader participant group

When a patient attempts to engage in physical or cognitive exertion, they demand ATP that simply isn't available, triggering a severe metabolic crash known as post-exertional malaise (PEM)

In CKD patients, the glomerular filtration rate (GFR) falls below 60 ml/min per 1.73 m 2 , eventually leading to kidney failure (Webster et al

AGEs accumulate in myocardial tissue and create covalent bonds with substances like collagen, causing an increase in collagen formation, aggravated myocardial fibrosis, and promotion of aortic sclerosis