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The International Union of Basic and Clinical Pharmacology, The British Pharmacological Society, The University of Edinburgh

Expert guidance can make a big difference

When extended follow-up data were analyzed, the trend accelerated: those who remained off therapy for a full year recovered approximately 50% of their initial weight loss

In contrast, the risk for right heart failure among those using GLP-1 receptor agonists did not significantly differ from the risk among those not using GLP-1 receptor agonists

That suggests that when used for obesity, these drugs are intended for long-term use, even after people reach their target weight