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The human dopamine transporter (hDAT) contains a high-affinity, extracellular, and allosteric Zn 2+ (zinc ion) binding site which, upon zinc binding, inhibits dopamine reuptake, inhibits amphetamine-induced hDAT internalization, and amplifies amphetamine-induced dopamine efflux

Since decreased Parasutterella relative abundance may accompany increased stress 80,81 , the increased Parasutterella relative abundance that occurred in this study following diet switch likely arose from the weight loss-mediated negative energy state

Department of Energy (DOE) Office of Science administers the programs and awards projects in technology areas across the entire department

In 1980 Jean-Pierre Raufman, a young gastroenterologist (figure 33), and John Pisano, a biochemist at the National Institute of Health with a fascination for venoms, began investigating the effect of peptides found in the saliva of the lizard on human physiology

The hmx1 mutant is unable to cause disease as this mutant is unable to grow in iron-limited conditions and has a defect in carbon monoxide production [186, 188]