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In cases of hypothyroidism , the thyroid gland becomes underactive , which can significantly slow down all the functions directly affected by its hormones, and can be triggered by Hashimotos thyroiditis

By combining the crystallographic analysis with computer modeling, we were able to throw further light on the mechanism of action of S

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Increased Gb3 expression and lipid accumulation in GLA-KO human iPSC kidney organoids Next, to determine the accumulation of Gb3, a main pathological mechanism in human Fabry disease 6,7 , confocal microscopy was performed, which revealed extensive accumulation of Gb3 in podocytes and tubular cells in GLA-mutant human iPSC kidney organoids (Fig

Glutathione peroxidase 1 Glutathione peroxidase 1 , also known as GPx1 , is an enzyme that in humans is encoded by the GPX1 gene on chromosome 3