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Braunwald E, Saberi S, Abraham TP, Elliott PM, Olivotto I (2023) Mavacamten: a first-in-class myosin inhibitor for obstructive hypertrophic cardiomyopathy, (in eng)

A methyl group makes the molecule non-polar, which means that it isnt able to mix with water and instead can pass through lipid membranes more easily

References 1 Growth Hormone & IGF ResearchLong-Arg3-IGF-1: structure, reduced IGF binding-protein affinity, and extended biological activity of the analog