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Insulin resistance can lead to type 2 diabetes or Pre diabetes if not managed

While statins remain first-line therapy for most patients according to ADA and ACC/AHA guidelines, some individuals may be taking niacin for specific indications such as severe hypertriglyceridemia or statin intolerance

Zorrilla-Vaca A, Rice D, Brown JK, Antonoff M, Sepesi B, Hofstetter W , Swisher S, Walsh G, Vaporciyan A, Mehran R, Hagberg C, Mena GE

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age, gender, diet, gut microbiome, disease subtype, concurrent medications) that determine the metabolic state of a patient and affect the overall drug response [83,84]