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JAMA 2017;318:360-70

It is one of the most essential metabolic functions of the body and is dependent upon a variety of enzymes

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What to expect at 4 weeks: Slight lightening or softening of uneven skin tone Improved skin hydration or smoother texture Some reduction in dullness or fatigue (if oxidative stress was high) Minimal but measurable improvement in antioxidant biomarkers Its important: at 4 weeks, changes are mild and gradual