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[1] Non-alcoholic fatty liver disease (NAFLD) represents a spectrum of liver conditions characterised by excessive fat accumulation in hepatocytes (liver cells) in individuals who consume little to no alcohol

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Excessive pyroptosis leads to rapid rupture of the plasma membrane and the excessive release of proinflammatory cytokines and chemokines, which results in neuroinflammation that triggers a cascade of secondary injuries culminating in neuronal death