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For example, a meta-analysis of 21 randomized, double-blind, placebo-controlled trials reported that 1.53 g/d of ALCAR significantly improved cognitive function assessed by a variety of methods in older adults with mild cognitive impairment or early Alzheimers disease [23]

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However, a phase 4 study conducted over a long period did not discover an elevated risk of bleeding associated with glutathione use

BPC-157 demonstrates neuroprotective effects across traumatic brain injury, stroke, spinal cord injury, and peripheral nerve damage in animal models

Its primary pharmacological characterization was published in European Journal of Endocrinology (PMID 9849822), where the authors identified it as the first growth-hormone-secretagogue receptor (GHSR-1a) agonist achieving GH-release selectivity comparable to GHRH in animal models